Vitamins B12 & D: Essential Support for Focus, Behavior, and Mood

Did you know Vitamin B12 and Vitamin D are key for children’s brain development and mental health? These nutrients support attention, behavioral regulation, and emotional balance, making them critical for kids and teens.

Why Families Are Interested

• Supports focus, attention, and learning by aiding neurotransmitter production

• Promotes emotional and behavioral regulation, reducing mood swings and hyperactivity

• Reduces inflammation and supports neurodevelopment, protecting long-term brain health

Who Might Benefit

• Children and teens with ADHD, anxiety, low mood, or behavioral challenges

• Families seeking integrative, natural strategies to enhance mental health and focus
  

B12 and D are foundational nutrients that can help children and teens regulate behavior, improve attention, and feel more emotionally balanced within a personalized integrative plan.

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References

1. Vitamin B12, Folate, Homocysteine, Inflammatory Mediators (Interleukin-6, Tumor Necrosis Factor-Α and C-Reactive Protein) Levels in Adolescents With Anxiety or Depressive Symptoms. Tan Y, Zhou L, Huang J, et al. Neuropsychiatr Dis Treat. 2023;19:785-800. doi:10.2147/NDT.S399378.
2. Association of Low Vitamin B12 Levels With Depressive and Schizophrenia Spectrum Disorders in Child and Adolescent Psychiatric Inpatients. Anmella G, Varela E, Prades N, et al. Eur Child Adolesc Psychiatry. 2025;:10.1007/s00787-025-02662-4. doi:10.1007/s00787-025-02662-4. New Research
3. Causal Relationship Between B Vitamins and Neuropsychiatric Disorders: A Systematic Review and Meta-Analysis. Ye M, Yang X, Yan J, et al. Neurosci Biobehav Rev. 2025;170:106068. doi:10.1016/j.neubiorev.2025.106068. Leading Journal New Research
4. Neuropsychiatric Manifestations in Vitamin B12 Deficiency. Sahu P, Thippeswamy H, Chaturvedi SK. Vitamins Horm. 2022;119:457-470. doi:10.1016/bs.vh.2022.01.001.
5. Modifiable Nutritional Biomarkers in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Vitamin D, B12, and Homocysteine Exposure Spanning Prenatal Development Through Late Adolescence. Avram OE, Bratu EA, Curis C, Moroianu LA, Drima E. Int J Mol Sci. 2025;26(9):4410. doi:10.3390/ijms26094410. New Research
6. Annual Research Review: Micronutrients and Their Role in the Treatment of Paediatric Mental Illness. Rucklidge JJ, Bruton A, Welsh A, Ast H, Johnstone JM. J Child Psychol Psychiatry. 2025;66(4):477-497. doi:10.1111/jcpp.14091. Leading Journal New Research
7. The Influence of Vitamin D Intake and Status on Mental Health in Children: A Systematic Review. Głąbska D, Kołota A, Lachowicz K, et al. Nutrients. 2021;13(3):952. doi:10.3390/nu13030952.
8. Molecular Basis Underlying the Therapeutic Potential of Vitamin D for the Treatment of Depression and Anxiety. Kouba BR, Camargo A, Gil-Mohapel J, Rodrigues ALS. Int J Mol Sci. 2022;23(13):7077. doi:10.3390/ijms23137077.
9. Effect of Vitamin D3 Supplementation in the First 2 Years of Life on Psychiatric Symptoms at Ages 6 to 8 Years: A Randomized Clinical Trial. Sandboge S, Räikkönen K, Lahti-Pulkkinen M, et al. JAMA Netw Open. 2023;6(5):e2314319. doi:10.1001/jamanetworkopen.2023.14319. Leading Journal
10. Low 25(oh)-Vitamin D Concentrations Are Associated With Emotional and Behavioral Problems in German Children and Adolescents. Husmann C, Frank M, Schmidt B, et al. PLoS One. 2017;12(8):e0183091. doi:10.1371/journal.pone.0183091.
11. Vitamin B12, Folic Acid, Homocysteine and Vitamin D Levels in Children and Adolescents With Obsessive Compulsive Disorder. Esnafoğlu E, Yaman E. Psychiatry Res. 2017;254:232-237. doi:10.1016/j.psychres.2017.04.032.